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Karyopharm Therapeutics Inc. (KPTI) Short Selling Data Suggests Potential Short Squeeze

In the past 20 years (since 2005 with the introduction of RegSho), short selling has come under scrutiny as millions of retail investors have discovered what we have been highlighting since early 2005. Market makers abuse the “market maker’s exemption” and short excessive amounts of shares in your stock without locating, borrowing, paying the rebate or the interest rate to borrow. They are required to cover on the same trading day, and our data proves they do not.

The chart below shows “Daily Short Volume” in Karyopharm Therapeutics Inc. (KPTI), and includes both EXEMPT (market makers) and NON-EXEMPT (everyone else) short sales. We consolidate the tape of all 14 US stock exchanges and purchase the “sell short” trade identifier data directly from the exchanges on a daily basis. This complete view of the trading in your stock shows a vastly different picture than “Total Short Interest”, which only includes non-exempt short sales that have not been covered by the twice per month reporting date. Unfortunately, this misses the majority of the short selling.

This indicates that a Short Squeeze may be starting in shares of Karyopharm Therapeutics Inc. at $5.58, after crossing above the $5.502 Trigger Price. This could signal a buying opportunity, given the right market conditions.

You can find the full report at https://www.woprai.com/

Please find the applicable data below, drawn from all major market providers.
DateShort VolumeTotal VolumePercentageSqueeze Trigger$ Value
2025-08-1432,894154,84221.244.51148,352
2025-08-1339,963144,58327.644.38175,038
2025-08-1264,074183,55434.913.96253,733
2025-08-11150,179300,78949.933.81572,182
2025-08-0844,38490,78248.893.96175,761
2025-08-07103,678211,42349.044.05419,896
2025-08-0634,168103,90732.883.98135,989
2025-08-0547,230108,62143.484188,920
2025-08-0413,73627,55049.863.9754,532
2025-08-0133,54664,13252.313.91131,165
2025-07-3156,174116,48948.223.88217,955
2025-07-3025,01043,71057.224.13103,291
2025-07-2933,90086,49639.194.14140,346
2025-07-2824,73550,74548.744.32106,855
2025-07-2530,45648,36562.974.41134,311
2025-07-24100,274209,98047.754.6461,260
2025-07-23380,881607,21662.734.541,729,200
2025-07-2253,567152,73935.073.93210,518
2025-07-2146,592105,11344.334.04188,232
2025-07-1887,879151,64357.954.04355,031
2025-07-1781,515152,42153.484.06330,951
2025-07-1639,87796,32941.44.16165,888
2025-07-15117,847250,36247.074.36513,813
2025-07-1499,887337,23329.624.63462,477
2025-07-11555,7431,735,70532.024.062,256,317
2025-07-1014,76277,07119.154.8872,039
2025-07-097,38343,38617.024.7434,995
2025-07-0861,414177,56334.594.55279,434
2025-07-0728,10563,43744.34.41123,943
2025-07-0310,05034,84228.844.5645,828
2025-07-0238,509112,65334.184.63178,297
2025-07-0114,02634,61940.524.3761,294
2025-06-3036,98674,98249.334.34160,519
2025-06-2714,71932,78844.894.3964,616
2025-06-2611,12238,34129.014.4749,715
2025-06-2518,93937,95349.94.5285,604
2025-06-2422,55945,69549.374.53102,192
 
Total885,633,4492,168,503,41440.845.54,872,773,145
 
* Totals include all data records back to 2020-08-17 00:00:00, data set is truncated for viewing.